A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice

Study Purpose

The purpose of this study is to evaluate treatment persistence with guselkumab and interleukin-17 inhibitor (IL-17i) initiated at enrollment into this study (PsABIOnd).

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

Unknown
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Observational
Eligible Ages 18 Years and Over
Gender All
More Inclusion & Exclusion Criteria

Inclusion Criteria:

Main study:
  • - Have a confirmed diagnosis of PsA as determined by a rheumatologist with reference to Classification criteria for Psoriatic Arthritis (CASPAR) - Start guselkumab or any approved interleukin-17 inhibitor (IL-17i) as a first, second, third, or fourth line of biologic disease-modifying antirheumatic drugs (bDMARD) therapy for the indication of PsA as part of standard clinical practice (according to local label, local regulations, and/or reimbursement requirements) at the time of enrollment into the observational study or within a maximum of 2 months after the initial baseline visit or after repeated baseline data collection.
  • - Sign a participation agreement/Informed consent form (ICF) allowing data collection and source data verification in accordance with local requirements.
  • - Able to read, understand, and intend to comply with completion of all Electronic patient-reported outcome (ePRO) instruments.
  • - The treatment decision must be taken by the participating rheumatologist prior to, and independently of the participant's inclusion into the study, following clinical practice in accordance with local and overarching guidelines and local regulations.
Substudy:
  • - Must sign the substudy ICF allowing data collection in accordance with local requirements.
  • - Is scheduled to receive guselkumab or IL-17i, per routine clinical practice, in the main study.
  • - Currently using or is willing to use wearables and/or commercial applications to track their disease within the course of their normal daily activities.

Exclusion Criteria:

Main study:
  • - Start guselkumab or an IL-17i therapy as fifth or further line of biologic treatment.
  • - Have already taken a specific IL-17i or IL-23i treatment and are planning on re-taking that specific treatment again.
  • - Unwilling or unable to participate in long-term data collection.
  • - Received an investigational drug (including investigational vaccines) or used an invasive investigational medical device within 30 days before the start of the study (that is, signing of informed consent) - Currently enrolled in any interventional study or any Janssen-sponsored observational clinical study (contemporary participation into observational studies or registries not sponsored by Janssen is acceptable) Substudy: - Have an insufficient command of language to interact effectively with the smartphone application, in the opinion of the investigator at each site.
  • - Any condition for which, in the opinion of the investigator, participation would not be in the best interest of the patient (example, compromise the well-being) or that could prevent, limit, or confound assessment.
- Unwilling or unable to comply with substudy assessments

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT05049798
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Janssen Pharmaceutica N.V., Belgium
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

Janssen Pharmaceutica N.V., Belgium Clinical Trial
Principal Investigator Affiliation Janssen Pharmaceutica N.V., Belgium
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Industry
Overall Status Recruiting
Countries Argentina, Australia, Austria, Belgium, Brazil, Canada, Colombia, France, Germany, Greece, Italy, Japan, Korea, Republic of, Mexico, Netherlands, Russian Federation, Spain, Sweden, Taiwan, United Kingdom
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

Arthritis, Psoriatic
Additional Details

Psoriatic arthritis (PsA) is a seronegative inflammatory spondylarthritis associated with psoriasis (PsO), which can cause pain and swelling in the joints, sausage-shaped swelling of the fingers and toes (dactylitis), inflammation of the muscle- or tendon insertions at adjacent bone (enthesitis), as well as raised red patches or various other expressions of psoriasis on the skin. Guselkumab (TREMFYA) is a fully human immunoglobulin G1 lambda (IgG1) monoclonal antibody (mAb) that binds to the p19 subunit of human interleukin (IL) 23 with high specificity and affinity, blocking IL-23 binding. Binding of guselkumab to the IL-23p19 subunit blocks the subsequent binding of extracellular IL-23 to the cell surface IL-23 receptor, inhibiting IL-23 specific intracellular signaling and subsequent activation and cytokine production. Participants with confirmed diagnosis of PsA who are starting guselkumab or any marketed interleukin-17 inhibitor (IL-17i) as a first, second, third, or fourth line of PsA biologic therapy per standard clinical practice will be enrolled in the main study. The aim of main study is to document the use of guselkumab and approved IL-17i therapies in routine clinical practice in patients with PsA who are starting guselkumab or an IL-17i as a first, second, third, or fourth line of biologic disease-modifying antirheumatic drugs (bDMARD) therapy. The overall duration of the main study, including recruitment and follow-up, is expected to be about 6 years. Participants who are starting guselkumab or an IL-17i treatment per routine clinical practice in the main study, and who meet the selection criteria for both the main study and substudy, will be consecutively offered entry into the substudy (a select number) at the time of enrollment into the main study. The substudy aims to collect additional data, continuously or with increased frequency, on the impact of guselkumab or IL-17i on patient mood, physical activity, sleep disturbance, disease symptoms, and health-related quality-of-life (HRQoL). Total duration of the substudy will be approximately 26-30 weeks consisting of a pre-treatment period of up to 14 days before the first dose of guselkumab or IL-17i in the main study and a 24-week (plus [+] up to 4 weeks follow-up) observation period.

Arms & Interventions

Arms

: Cohort 1: Guselkumab

Data as available from participant's source medical records will be collected for adult participants with a confirmed diagnosis of Psoriatic Arthritis (PsA) who are starting guselkumab as a first, second, third, or fourth line of PsA biologic therapy either as monotherapy or with other medications per routine clinical practice in main study. Participants who meet the selection criteria for both the main study and substudy, will be consecutively offered to be enrolled into the substudy at the time of enrollment into the main study.

: Cohort 2: Interleukin-17 inhibitor (IL-17i)

Data as available from participant's source medical records will be collected for adult participants with a confirmed diagnosis of PsA who are starting IL-17i as a first, second, third, or fourth line of PsA biologic therapy either as monotherapy or with other medications per routine clinical practice in main study. Participants who meet the selection criteria for both the main study and substudy, will be consecutively offered to be enrolled into the substudy at the time of enrollment into the main study.

Interventions

Drug: - Guselkumab

Participants will not receive any intervention as a part of this study. Participants who are initiating the treatment with guselkumab, will be observed according to standard clinical practice.

Drug: - IL-17i

Participants will not receive any intervention as a part of this study. Participants who are initiating the treatment with IL-17i, will be observed according to standard clinical practice.

Contact a Trial Team

If you are interested in learning more about this trial, find the trial site nearest to your location and contact the site coordinator via email or phone. We also strongly recommend that you consult with your healthcare provider about the trials that may interest you and refer to our terms of service below.

International Sites

Hospital Italiano de Buenos Aires, Buenos Aires, Argentina

Status

Not yet recruiting

Address

Hospital Italiano de Buenos Aires

Buenos Aires, , C1199ABB

Hospital J. M. Ramos Mejía, Buenos Aires, Argentina

Status

Not yet recruiting

Address

Hospital J. M. Ramos Mejía

Buenos Aires, , C1221ADC

Psoriahue, Caba, Argentina

Status

Withdrawn

Address

Psoriahue

Caba, , C1425 DKG

Ciudad Autonoma de Buenos Aires, Argentina

Status

Withdrawn

Address

Hospital Militar Central Cir. My. Dr. Cosme Argerich

Ciudad Autonoma de Buenos Aires, , C1426BOR

OMI, Ciudad Autónoma de Buenos Aires, Argentina

Status

Not yet recruiting

Address

OMI

Ciudad Autónoma de Buenos Aires, , C1015ABO

Hospital Cordoba, Córdoba, Argentina

Status

Not yet recruiting

Address

Hospital Cordoba

Córdoba, , 5000

MR-Medicina Reumatológica, San Fernando, Buenos Aires, Argentina

Status

Not yet recruiting

Address

MR-Medicina Reumatológica

San Fernando, Buenos Aires, , B1646

The Queen Elizabeth Hospital, Adelaide, Australia

Status

Not yet recruiting

Address

The Queen Elizabeth Hospital

Adelaide, , 5011

Royal North Shore Hospital, St Leonards, Australia

Status

Not yet recruiting

Address

Royal North Shore Hospital

St Leonards, , 2065

Barmherzige Brüder Krankenhaus Graz, Graz, Austria

Status

Withdrawn

Address

Barmherzige Brüder Krankenhaus Graz

Graz, , 8020

LKH-Univ. Klinikum Graz, Graz, Austria

Status

Not yet recruiting

Address

LKH-Univ. Klinikum Graz

Graz, , 8036

Praxis Prim. Priv.Doz. Dr. Burkhard Leeb, Hollabrunn, Austria

Status

Withdrawn

Address

Praxis Prim. Priv.Doz. Dr. Burkhard Leeb

Hollabrunn, , 2020

Kepler Universitätsklinikum GmbH, Linz, Austria

Status

Recruiting

Address

Kepler Universitätsklinikum GmbH

Linz, , 4021

LK Weinviertel Stockerau, Stockerau, Austria

Status

Withdrawn

Address

LK Weinviertel Stockerau

Stockerau, , 2000

Medizinische Universität Wien, Vienna, Austria

Status

Recruiting

Address

Medizinische Universität Wien

Vienna, , 1090

Wien, Austria

Status

Recruiting

Address

Evang. Krankenhaus Gemein. Betriebgesm. Mbh

Wien, , A-1100

AZ Sint-Jan, Brugge, Belgium

Status

Not yet recruiting

Address

AZ Sint-Jan

Brugge, , 8000

Hopital Erasme, Brussel, Belgium

Status

Not yet recruiting

Address

Hopital Erasme

Brussel, , 1070

Reumaclinic Genk-Hasselt, Genk, Belgium

Status

Not yet recruiting

Address

Reumaclinic Genk-Hasselt

Genk, , 3600

UZ Leuven, Leuven, Belgium

Status

Not yet recruiting

Address

UZ Leuven

Leuven, , 3000

Liège, Belgium

Status

Not yet recruiting

Address

CHU de Liège - Domaine Universitaire du Sart Tilman

Liège, , 4000

EDUMED, Curitiba, Brazil

Status

Not yet recruiting

Address

EDUMED

Curitiba, , 80440-080

CMiP - Centro Mineiro de Pesquisa, Juiz de Fora, Brazil

Status

Not yet recruiting

Address

CMiP - Centro Mineiro de Pesquisa

Juiz de Fora, , 36010-570

Riverside Professional Center, Sydney, Nova Scotia, Canada

Status

Not yet recruiting

Address

Riverside Professional Center

Sydney, Nova Scotia, B1S 3N1

The Waterside Clinic, Barrie, Ontario, Canada

Status

Not yet recruiting

Address

The Waterside Clinic

Barrie, Ontario, L4M 6L2

Private Practice - Dr. Pauline Boulos, Dundas, Ontario, Canada

Status

Not yet recruiting

Address

Private Practice - Dr. Pauline Boulos

Dundas, Ontario, L9H 1B7

Mississauga, Ontario, Canada

Status

Not yet recruiting

Address

Brandusa Florica Medicine Professional Corporation

Mississauga, Ontario, L5A 3V8

Windsor, Ontario, Canada

Status

Not yet recruiting

Address

Dr. Sabeen Anwar Medicine Professional Corporation

Windsor, Ontario, N8X 1T3

Montreal, Quebec, Canada

Status

Not yet recruiting

Address

CIUSSS de l'Est-de-l'Île-de-Montréal Installation Hôpital Maisonneuve-Rosemont

Montreal, Quebec, H1T 2M4

Centre de Recherche Musculo Squelettique, Trois Rivieres, Quebec, Canada

Status

Not yet recruiting

Address

Centre de Recherche Musculo Squelettique

Trois Rivieres, Quebec, G8Z1Y2

Community Rheumatology Care, Saskatoon, Saskatchewan, Canada

Status

Not yet recruiting

Address

Community Rheumatology Care

Saskatoon, Saskatchewan, S7K 0H6

Rheumatology Associates of Saskatoon, Saskatoon, Saskatchewan, Canada

Status

Not yet recruiting

Address

Rheumatology Associates of Saskatoon

Saskatoon, Saskatchewan, S7K 0H6

Ancaster Medical Centre, Ancaster, Canada

Status

Withdrawn

Address

Ancaster Medical Centre

Ancaster, , L9G 3K9

Quebec, Canada

Status

Not yet recruiting

Address

G.R.M.O. (Groupe de recherche en maladies osseuses) Inc.

Quebec, , G1V 3M7

Sherbrooke, Canada

Status

Not yet recruiting

Address

Centre Hospitalier Universitaire de Sherbrooke

Sherbrooke, , J1H 5N4

Artus Health Centre, Vancouver, Canada

Status

Not yet recruiting

Address

Artus Health Centre

Vancouver, , V5Z 1J9

Manitoba Clinic, Winnipeg, Canada

Status

Not yet recruiting

Address

Manitoba Clinic

Winnipeg, , R3A 1M3

Circaribe Sas, Barranquilla, Colombia

Status

Not yet recruiting

Address

Circaribe Sas

Barranquilla, , 080002

Funcentra, Montería, Colombia

Status

Not yet recruiting

Address

Funcentra

Montería, , 230002

Hôpital Avicenne, Bobigny, France

Status

Not yet recruiting

Address

Hôpital Avicenne

Bobigny, , 93000

Hôpital Pellegrin CHU Bordeaux, Bordeaux, France

Status

Withdrawn

Address

Hôpital Pellegrin CHU Bordeaux

Bordeaux, ,

Hôpital Gabriel Montpied, Clermont Ferrand, France

Status

Recruiting

Address

Hôpital Gabriel Montpied

Clermont Ferrand, , 63003

Creteil, France

Status

Not yet recruiting

Address

Centre Hospitalier Universitaire(CHU) - Hopital Henri Mondor

Creteil, , 94000

CHU Grenoble, Echirolles, France

Status

Recruiting

Address

CHU Grenoble

Echirolles, , 38130

Levallois Perret, France

Status

Recruiting

Address

Hertford British Hospital Corporation - Institut Hospitalier

Levallois Perret, , 92300

Lille, France

Status

Recruiting

Address

CHRU HOPITAL ROGER SALENGRO Consultation Appareil locomoteur

Lille, , 59037

Hôpital Saint Roch, Nice, France

Status

Not yet recruiting

Address

Hôpital Saint Roch

Nice, , 6006

Orléans, France

Status

Not yet recruiting

Address

CHR Orléans - Nouvel Hôpital Orléans La Source

Orléans, , 45032

Paris, France

Status

Not yet recruiting

Address

Hôpital Lariboisière - Centre Viggo Petersen

Paris, , 75010

Hopital Saint-Antoine, Paris, France

Status

Not yet recruiting

Address

Hopital Saint-Antoine

Paris, , 75012

Hôpital Pitié-Salpétrière, Paris, France

Status

Not yet recruiting

Address

Hôpital Pitié-Salpétrière

Paris, , 75651

CHRU Hôpital de Hautepierre, Strasbourg Cedex, France

Status

Not yet recruiting

Address

CHRU Hôpital de Hautepierre

Strasbourg Cedex, , 67098

Hopital Purpan, Toulouse, France

Status

Not yet recruiting

Address

Hopital Purpan

Toulouse, , 31059

Praxis für Rheumatologie, Amberg, Germany

Status

Recruiting

Address

Praxis für Rheumatologie

Amberg, , 92224

Rheuma-Praxis Bayreuth, Bayreuth, Germany

Status

Recruiting

Address

Rheuma-Praxis Bayreuth

Bayreuth, , 95444

Rheumatologische Schwerpunktpraxis, Berlin, Germany

Status

Recruiting

Address

Rheumatologische Schwerpunktpraxis

Berlin, , 12161

Burghausen, Germany

Status

Withdrawn

Address

Schwerpunktpraxis für Rheumatologie und Klinische Immunologi

Burghausen, , 84489

Universitätsklinikum Düsseldorf, Dusseldorf, Germany

Status

Recruiting

Address

Universitätsklinikum Düsseldorf

Dusseldorf, , 40225

Service Rheuma Erfurt, Erfurt, Germany

Status

Not yet recruiting

Address

Service Rheuma Erfurt

Erfurt, , 99096

Universitatsklinikum Frankfurt, Frankfurt, Germany

Status

Not yet recruiting

Address

Universitatsklinikum Frankfurt

Frankfurt, , 60590

Rheumapraxis Dr. Liebhaber, Halle-Saale, Germany

Status

Recruiting

Address

Rheumapraxis Dr. Liebhaber

Halle-Saale, , 6128

Hamburg, Germany

Status

Recruiting

Address

Praxis fur Klinische Studien und Praxis fur Orthopadie

Hamburg, , 22415

Rheumatologie im Struenseehaus, Hamburg, Germany

Status

Recruiting

Address

Rheumatologie im Struenseehaus

Hamburg, , 22767

Rheumazentrum Ruhrgebiet, Herne, Germany

Status

Recruiting

Address

Rheumazentrum Ruhrgebiet

Herne, , 44649

Krankenhaus Porz am Rhein, Koln, Germany

Status

Recruiting

Address

Krankenhaus Porz am Rhein

Koln, , 51149

Rheumatologische Praxis, Leipzig, Germany

Status

Recruiting

Address

Rheumatologische Praxis

Leipzig, , 04109

Rheumatologische Praxis, Magdeburg, Germany

Status

Recruiting

Address

Rheumatologische Praxis

Magdeburg, , 39104

Praxiszentrum St. Bonifatius, München, Germany

Status

Recruiting

Address

Praxiszentrum St. Bonifatius

München, , 81541

Praxis Thilo Klopsch, Neubrandenburg, Germany

Status

Recruiting

Address

Praxis Thilo Klopsch

Neubrandenburg, , 17033

Püttlingen, Germany

Status

Not yet recruiting

Address

Knappschaftsklinikum Saar GmbH Klinik für Rheumatologie

Püttlingen, , 66346

Rheumazentrum Ratingen, Ratingen, Germany

Status

Recruiting

Address

Rheumazentrum Ratingen

Ratingen, , 40878

Templin, Germany

Status

Recruiting

Address

Rheumatologisch-immunologische Arztpraxis

Templin, , 17268

Vogelsang-Gommern, Germany

Status

Recruiting

Address

Immunologisches Zentrum Vogelsang-Gommern GmbH

Vogelsang-Gommern, , 39245

Krankenhaus St. Josef, Wuppertal, Germany

Status

Not yet recruiting

Address

Krankenhaus St. Josef

Wuppertal, , 42105

Athens Navy Hospital, Athens, Greece

Status

Not yet recruiting

Address

Athens Navy Hospital

Athens, , 11521

General Hospital 'Gennimatas', Athens, Greece

Status

Not yet recruiting

Address

General Hospital 'Gennimatas'

Athens, , 11527

Laiko General Hospital of Athens, Athens, Greece

Status

Not yet recruiting

Address

Laiko General Hospital of Athens

Athens, , 11527

Laiko General Hospital of Athens, Athens, Greece

Status

Withdrawn

Address

Laiko General Hospital of Athens

Athens, , 11527

Patras, Greece

Status

Not yet recruiting

Address

University General Hospital of Rio Patras

Patras, , 26500

Patra, Greece

Status

Not yet recruiting

Address

'Agios Andreas' General Hospital of Patras

Patra, , 263 32

Ippokrateio Hospital, Thessaloniki, Greece

Status

Not yet recruiting

Address

Ippokrateio Hospital

Thessaloniki, , 546 42

Bari, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliero Universitaria Consorziale Policlinico di Bari

Bari, , 70124

Campobasso, Italy

Status

Not yet recruiting

Address

Ospedale Regionale Cardarelli-Università degli Studi del Mol

Campobasso, , 86100

Universita della Magna grecia, Catanzaro, Italy

Status

Not yet recruiting

Address

Universita della Magna grecia

Catanzaro, , 88100

AOU Careggi, Firenze, Italy

Status

Not yet recruiting

Address

AOU Careggi

Firenze, , 50141

Napoli, Italy

Status

Not yet recruiting

Address

Seconda Univesità degli Studi di Napoli, AOU

Napoli, , 80131

University of Padova, Padova, Italy

Status

Not yet recruiting

Address

University of Padova

Padova, , 35128

Palermo, Italy

Status

Recruiting

Address

Azienda Ospedaliero Universitaria Policlinico Paolo Giaccone

Palermo, , 90127

Azienda Ospedaliero Universitaria Pisana, Pisa, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliero Universitaria Pisana

Pisa, , 56126

Universita Cattolica del Sacro Cuore, Rome, Italy

Status

Not yet recruiting

Address

Universita Cattolica del Sacro Cuore

Rome, , 20123

Istituto Clinico Humanitas, Rozzano, Italy

Status

Recruiting

Address

Istituto Clinico Humanitas

Rozzano, , 20156

Torino, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera Città della Salute e della Scienza di Torino

Torino, , 10126

Udine, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliero Universitaria S.Maria Della Misericordia

Udine, , 33100

Verona, Italy

Status

Not yet recruiting

Address

Azienda Ospedaliera Universitaria Integrata Verona

Verona, , 37067

Kita-harima Medical Center, Hyogo, Japan

Status

Not yet recruiting

Address

Kita-harima Medical Center

Hyogo, , 6751392

Meguro-ku, Japan

Status

Not yet recruiting

Address

Toho University Medical Center, Ohashi Hospital

Meguro-ku, , 153-8515

Osaka Metropolitan University Hospital, Osaka, Japan

Status

Not yet recruiting

Address

Osaka Metropolitan University Hospital

Osaka, , 545-8586

Hokkaido University Hospital, Sapporo, Japan

Status

Not yet recruiting

Address

Hokkaido University Hospital

Sapporo, , 060-8648

Kyorin University Hospital, Tokyo, Japan

Status

Not yet recruiting

Address

Kyorin University Hospital

Tokyo, , 181-8611

Cheonan-si, Korea, Republic of

Status

Not yet recruiting

Address

Soonchunhyang University Cheonan Hospital

Cheonan-si, , 31151

Seoul, Korea, Republic of

Status

Not yet recruiting

Address

Seoul Metropolitan Government Seoul National University Boramae Medical Center

Seoul, , 07061

Consultorio de Reumatologia, Mexico, Mexico

Status

Not yet recruiting

Address

Consultorio de Reumatologia

Mexico, , 07760

Medical Care & Research SA de CV, Mérida, Mexico

Status

Not yet recruiting

Address

Medical Care & Research SA de CV

Mérida, , 97070

Hospital Puerta de Hierro, Zapopan, Mexico

Status

Not yet recruiting

Address

Hospital Puerta de Hierro

Zapopan, , 45116

Amsterdam, Netherlands

Status

Not yet recruiting

Address

Academisch Medisch Centrum Universiteit van Amsterdam

Amsterdam, , 1105 AZ

Medisch Spectrum Twente, Enschede, Netherlands

Status

Not yet recruiting

Address

Medisch Spectrum Twente

Enschede, , 7500 KA

Universitair Medisch Centrum Groningen, Groningen, Netherlands

Status

Not yet recruiting

Address

Universitair Medisch Centrum Groningen

Groningen, , 9700 RB

Elkerliek Ziekenhuis, Helmond, Netherlands

Status

Not yet recruiting

Address

Elkerliek Ziekenhuis

Helmond, , 5707 HA

Sint Maartenskliniek Orthopedic Center, Nijmegen, Netherlands

Status

Not yet recruiting

Address

Sint Maartenskliniek Orthopedic Center

Nijmegen, , 6522 JV

SBEU HPE Kemerovo State Medical Academy, Kemerovo, Russian Federation

Status

Terminated

Address

SBEU HPE Kemerovo State Medical Academy

Kemerovo, , G4 0SF

Moscow, Russian Federation

Status

Terminated

Address

Bakoulev Scientific Center For Cardiovascular Surgery Rams

Moscow, , 121552

Moscow, Russian Federation

Status

Terminated

Address

FGBU Research Institute of Rheumatology named V.A.Nasonova

Moscow, , 190068

Petrozavodsk, Russian Federation

Status

Withdrawn

Address

Republican Hospital named by V.A.Baranova

Petrozavodsk, , 185019

Saint Petersburg, Russian Federation

Status

Withdrawn

Address

North-Western State Medical University named I.I. Mechnikov

Saint Petersburg, ,

City Hospital #3, Tomsk, Russian Federation

Status

Terminated

Address

City Hospital #3

Tomsk, , 634045

Hosp. Univ. A Coruña, A Coruña, Spain

Status

Not yet recruiting

Address

Hosp. Univ. A Coruña

A Coruña, , 15006

Hosp. Clinic I Provincial de Barcelona, Barcelona, Spain

Status

Recruiting

Address

Hosp. Clinic I Provincial de Barcelona

Barcelona, , 08036

Hosp. Univ. de Basurto, Bilbao, Spain

Status

Recruiting

Address

Hosp. Univ. de Basurto

Bilbao, , 48013

Hosp. Gral. Univ. de Castellon, Castellon, Spain

Status

Withdrawn

Address

Hosp. Gral. Univ. de Castellon

Castellon, , 12004

Hosp. Reina Sofia, Córdoba, Spain

Status

Not yet recruiting

Address

Hosp. Reina Sofia

Córdoba, , 14004

Hosp. Gral. Univ. de Elche, Elche, Spain

Status

Withdrawn

Address

Hosp. Gral. Univ. de Elche

Elche, , 03203

Complejo hospitalario de Granada, Granada, Spain

Status

Not yet recruiting

Address

Complejo hospitalario de Granada

Granada, , 18016

Hosp. Univ. 12 de Octubre, Madrid, Spain

Status

Not yet recruiting

Address

Hosp. Univ. 12 de Octubre

Madrid, , 28041

Hosp. Univ. de Getafe, Madrid, Spain

Status

Not yet recruiting

Address

Hosp. Univ. de Getafe

Madrid, , 28905

Hosp. Univ. Central de Asturias, Oviedo, Spain

Status

Not yet recruiting

Address

Hosp. Univ. Central de Asturias

Oviedo, , 33011

Hosp. Virgen Del Rocio, Sevilla, Spain

Status

Not yet recruiting

Address

Hosp. Virgen Del Rocio

Sevilla, , 41013

Sahlgrenska Universitetssjukhuset, Göteborg, Sweden

Status

Not yet recruiting

Address

Sahlgrenska Universitetssjukhuset

Göteborg, , 416 85

Universitetssjukhuset i Lund, Lund, Sweden

Status

Recruiting

Address

Universitetssjukhuset i Lund

Lund, , 221 00

Universitetssjukhuset Örebro, Orebro, Sweden

Status

Recruiting

Address

Universitetssjukhuset Örebro

Orebro, , 70185

Stockholm, Sweden

Status

Recruiting

Address

Akademiskt Specialistcentrum centrum för reumatologi

Stockholm, , 113 65

Akademiska Sjukhuset, Uppsala, Sweden

Status

Recruiting

Address

Akademiska Sjukhuset

Uppsala, , 75185

Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

Status

Not yet recruiting

Address

Kaohsiung Veterans General Hospital

Kaohsiung, , 81362

Chang Gung Medical Foundation, Kaohsiung, Taiwan

Status

Not yet recruiting

Address

Chang Gung Medical Foundation

Kaohsiung, , 83301

Taichung Veterans General Hospital, Taichung, Taiwan

Status

Not yet recruiting

Address

Taichung Veterans General Hospital

Taichung, ,

Aberdeen, United Kingdom

Status

Recruiting

Address

NHS Grampian - Aberdeen Royal Infirmary (ARI)

Aberdeen, , AB25 2ZB

Nevill Hall Hospital, Abergavenny, United Kingdom

Status

Recruiting

Address

Nevill Hall Hospital

Abergavenny, , NP7 7EG

University Hospital Monklands, Airdrie, United Kingdom

Status

Not yet recruiting

Address

University Hospital Monklands

Airdrie, , ML6 0JS

Wolfson Centre Royal United Hospitals, Bath, United Kingdom

Status

Recruiting

Address

Wolfson Centre Royal United Hospitals

Bath, , BA1 3NG

Cardiff University School of Medicine, Cardiff, United Kingdom

Status

Not yet recruiting

Address

Cardiff University School of Medicine

Cardiff, , CF14 4XN

Glasgow Royal Infirmary, Glasgow, United Kingdom

Status

Recruiting

Address

Glasgow Royal Infirmary

Glasgow, , 650029

Hull Royal Infirmary, Hull, United Kingdom

Status

Recruiting

Address

Hull Royal Infirmary

Hull, , HU3 2JZ

Chapel Allerton Hospital, Leeds, United Kingdom

Status

Recruiting

Address

Chapel Allerton Hospital

Leeds, , LS7 4SA

Kings College Hospital, London, United Kingdom

Status

Not yet recruiting

Address

Kings College Hospital

London, , SE5 9RS

Manchester, United Kingdom

Status

Not yet recruiting

Address

Central Manchester University Hospitals NHS Foundation Trust

Manchester, , M13 9WL

Newcastle Upon Tyne, United Kingdom

Status

Recruiting

Address

The Newcastle upon Tyne Hospitals NHS Trust - Freeman Hospit

Newcastle Upon Tyne, , NE7 7DN

Queen Alexandra Hospital, Portsmouth, United Kingdom

Status

Recruiting

Address

Queen Alexandra Hospital

Portsmouth, , PO6 3LY

Shirley Caldwell, Salford, United Kingdom

Status

Recruiting

Address

Shirley Caldwell

Salford, , M6 8HD

Southampton General Hospital, Southampton, United Kingdom

Status

Recruiting

Address

Southampton General Hospital

Southampton, , SO16 6YD

Haywood Hospital, Staffordshire, United Kingdom

Status

Not yet recruiting

Address

Haywood Hospital

Staffordshire, , ST6 7AG

Stamford and Rutland hospital, Stamford, United Kingdom

Status

Recruiting

Address

Stamford and Rutland hospital

Stamford, , PE9 1UA

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