The Effect of Psoriatic Arthritis on Female Sexual Dysfunction

Study Purpose

Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders.

Recruitment Criteria

Accepts Healthy Volunteers

Healthy volunteers are participants who do not have a disease or condition, or related conditions or symptoms

Yes
Study Type

An interventional clinical study is where participants are assigned to receive one or more interventions (or no intervention) so that researchers can evaluate the effects of the interventions on biomedical or health-related outcomes.


An observational clinical study is where participants identified as belonging to study groups are assessed for biomedical or health outcomes.


Searching Both is inclusive of interventional and observational studies.

Observational
Eligible Ages 20 Years - 40 Years
Gender Female
More Inclusion & Exclusion Criteria

Inclusion Criteria:

  • - The study will focuses on the relationship between the FSD and PsA; - The healthy controls will derive from a population within the same geographic area and ethnic background as PsA; - Used the same questionnaires/instruments of FSFI to diagnose FSD.

Exclusion Criteria:

  • - pregnancy, - breastfeeding.
  • - being sexually inactive.
  • - having a partner with sexual dysfunction, - refusing to participate, or.
  • - being unable to read.
- Females with any sexual transmitted disease

Trial Details

Trial ID:

This trial id was obtained from ClinicalTrials.gov, a service of the U.S. National Institutes of Health, providing information on publicly and privately supported clinical studies of human participants with locations in all 50 States and in 196 countries.

NCT06370221
Phase

Phase 1: Studies that emphasize safety and how the drug is metabolized and excreted in humans.

Phase 2: Studies that gather preliminary data on effectiveness (whether the drug works in people who have a certain disease or condition) and additional safety data.

Phase 3: Studies that gather more information about safety and effectiveness by studying different populations and different dosages and by using the drug in combination with other drugs.

Phase 4: Studies occurring after FDA has approved a drug for marketing, efficacy, or optimal use.

Lead Sponsor

The sponsor is the organization or person who oversees the clinical study and is responsible for analyzing the study data.

Egymedicalpedia
Principal Investigator

The person who is responsible for the scientific and technical direction of the entire clinical study.

N/A
Principal Investigator Affiliation N/A
Agency Class

Category of organization(s) involved as sponsor (and collaborator) supporting the trial.

Industry
Overall Status Not yet recruiting
Countries Egypt
Conditions

The disease, disorder, syndrome, illness, or injury that is being studied.

Psoriatic Arthritis
Additional Details

Psoriasis is one of the most common immunemediated chronic inflammatory skin disorders. Beside genetic factors, several environmental factors such as injuries, infections, stress, drugs, and immune defect take part in autoimmune pathogenesis of the disease. In addition, it has been reported that some hormones may also have a role in the pathogenesis of psoriasis, due to their effects on keratinocytes proliferation. Studies revealed that sex hormones manifest a variety of biological and immunological effects in the skin which modulate the natural course of psoriasis. Approximately 20-30% of patients with psoriasis may also have psoriatic arthritis, which often causes significant musculoskeletal pain that significantly impairs quality of life (QoL). Although sexual dysfunction is a common complaint, affecting 30 to 70% of psoriasis patients, few studies have analyzed the impact of psoriasis and psoriatic arthritis on quality of sexual life.

Arms & Interventions

Arms

: Group A: Cases Group

About 100 patient females suffering from Psoriatic arthritis and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients

: Group B: Control Group

About 80 healthy control females

Interventions

Behavioral: - The effect of psoriatic Arthritis

to assess the frequency rates of sexual problems and associated factors in a cohort of married females with Psoriatic arthritis, and to investigate the correlation between sex hormones profile ( estrogen and progesterone level) and female sexual function in Psoriatic arthritis patients.

Contact a Trial Team

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International Sites

Qena Hospital, Qinā, Egypt

Status

Address

Qena Hospital

Qinā, ,

Site Contact

Eisa Hegazy, Assist.Prof

eisa_mohamed4152@med.svu.edu.eg

01094337795

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